diff --git a/drivers/i2c/Kconfig b/drivers/i2c/Kconfig
index 46cde098c11c2fe993dea722f1dd37d0ec3c7498..e380c6eef3af6500edc94b3a8db668bb59dfa258 100644
--- a/drivers/i2c/Kconfig
+++ b/drivers/i2c/Kconfig
@@ -4,7 +4,6 @@
 
 menuconfig I2C
 	tristate "I2C support"
-	depends on !S390
 	select RT_MUTEXES
 	---help---
 	  I2C (pronounce: I-squared-C) is a slow serial bus protocol used in
@@ -76,6 +75,7 @@ config I2C_HELPER_AUTO
 
 config I2C_SMBUS
 	tristate "SMBus-specific protocols" if !I2C_HELPER_AUTO
+	depends on GENERIC_HARDIRQS
 	help
 	  Say Y here if you want support for SMBus extensions to the I2C
 	  specification. At the moment, the only supported extension is
diff --git a/drivers/i2c/busses/Kconfig b/drivers/i2c/busses/Kconfig
index a3725de923848baba3c55f3067588f42759b5227..adfee98486b159843b38ff107c8ea9dd25189ed5 100644
--- a/drivers/i2c/busses/Kconfig
+++ b/drivers/i2c/busses/Kconfig
@@ -114,7 +114,7 @@ config I2C_I801
 
 config I2C_ISCH
 	tristate "Intel SCH SMBus 1.0"
-	depends on PCI
+	depends on PCI && GENERIC_HARDIRQS
 	select LPC_SCH
 	help
 	  Say Y here if you want to use SMBus controller on the Intel SCH
@@ -543,6 +543,7 @@ config I2C_NUC900
 
 config I2C_OCORES
 	tristate "OpenCores I2C Controller"
+	depends on GENERIC_HARDIRQS
 	help
 	  If you say yes to this option, support will be included for the
 	  OpenCores I2C controller. For details see
@@ -777,7 +778,7 @@ config I2C_DIOLAN_U2C
 
 config I2C_PARPORT
 	tristate "Parallel port adapter"
-	depends on PARPORT
+	depends on PARPORT && GENERIC_HARDIRQS
 	select I2C_ALGOBIT
 	select I2C_SMBUS
 	help
@@ -802,6 +803,7 @@ config I2C_PARPORT
 
 config I2C_PARPORT_LIGHT
 	tristate "Parallel port adapter (light)"
+	depends on GENERIC_HARDIRQS
 	select I2C_ALGOBIT
 	select I2C_SMBUS
 	help